Umbralisib hydrochloride
CAS No. | 1532533-78-0 | Cat. No. | BCP24682 |
Name | Umbralisib hydrochloride | ||
Synonyms | RP5264 hydrochloride;TGR-1202 hydrochloride;TGR 1202 hydrochloride; TGR1202 hydrochloride; TGR-1202 HCl; TGR 1202 HCl; TGR1202 HCl; | ||
Formula | C31H25ClF3N5O3 | M. Wt | 608.01 |
Description | Umbralisib hydrochloride is a novel PI3Kδ inhibitor, with IC50 and EC50 of 22.2 nM and 24.3 nM, respectively; Umbralisib hydrochloride (TGR-1202 hydrochloride) is also active against CK1ε, with an EC50 value of 6.0 μM. | ||
Pathways | PI3K/Akt/mTOR | ||
Targets | PI3K |
Structure
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