Umbralisib hydrochloride

  • Chemical Properties
CAS No. 1532533-78-0 Cat. No. BCP24682
Name Umbralisib hydrochloride
Synonyms RP5264 hydrochloride;TGR-1202 hydrochloride;TGR 1202 hydrochloride; TGR1202 hydrochloride; TGR-1202 HCl; TGR 1202 HCl; TGR1202 HCl;
Formula C31H25ClF3N5O3 M. Wt 608.01
  • Biological Activity
Description Umbralisib hydrochloride is a novel PI3Kδ inhibitor, with IC50 and EC50 of 22.2 nM and 24.3 nM, respectively; Umbralisib hydrochloride (TGR-1202 hydrochloride) is also active against CK1ε, with an EC50 value of 6.0 μM.
Pathways PI3K/Akt/mTOR 
Targets PI3K 

Structure

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