Tebanicline tosylate

CAS No.	198283-74-8	Cat. No.	BCP25229
Name	Tebanicline tosylate
Synonyms	ABT594 tosylate;Tebanicline tosilate;
Formula	C16H19ClN2O4S	M. Wt	370.85

Description	Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
Related Products	209326-18-1（Tebanicline benzoate） 209326-19-2（Tebanicline dihydrochloride） 203564-54-9（Tebanicline HCl） 198283-73-7（Tebanicline）
Pathways	Ion Channel/Membrane Transporter
Targets	nAChR

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