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ABT-594 Chemical Structure

ABT-594

Data Sheet For research use only. Not for human use.
Cat. No. :BCP19181CAS No. :198283-73-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 198283-73-7 Cat. No. BCP19181
Related Products 203564-54-9(Tebanicline HCl) 209326-19-2(Tebanicline dihydrochloride) 209326-18-1(Tebanicline benzoate) 198283-74-8(Tebanicline tosylate)
Name ABT-594
Synonyms ABT594;ABT 594;Tebanicline;Ebanicline;
SMILES
Chemical Name
Formula C9H11ClN2O M. Wt 198.652
Purity 98% Storage Store at 4-8°C
Description Tebanicline, also known as ABT-594 and Ebanicline, a potent synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
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