XL-765

  • Chemical Properties
CAS No. 1123889-87-1 Cat. No. BCP32612
Name XL-765
Synonyms XL765;XL 765;SAR245409;SAR-245409;SAR 245409;Voxtalisib Analogue;
Formula C31H29N5O6S M. Wt 599.66
  • Biological Activity
Description XL765 Analogue is a dual inhibitor of mTOR/PI3K, mostly for p110γ with IC50 of 9 nM; also inhibits DNA-PK and mTOR. Phase 1/2.
Pathways PI3K/Akt/mTOR 
Targets PI3K mTOR 

Structure

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