NS19504
| CAS No. | 327062-46-4 | Cat. No. | BCP33054 |
| Name | NS19504 | ||
| Synonyms | NS 19504;NS-19504; | ||
| Formula | C10H9BrN2S | M. Wt | 269.16 |
| Description | NS19504 is a selective activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1) (EC50 = 11 μM). Activates BK channels in native smooth muscle cells from guinea pig bladder and reduces spontaneous phasic contractions in bladder strips ex vivo. Displays no effect on contractions induced by a high K+ concentration or at 65 other receptors tested, including L- and N- type Ca2+ channels, Nav, KATP and hERG channels. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel | ||
Structure
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