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NS19504 Chemical Structure

NS19504

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33054CAS No. :327062-46-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 327062-46-4 Cat. No. BCP33054
Name NS19504
Synonyms NS 19504;NS-19504;
SMILES C1=CC(=CC=C1CC2=CN=C(S2)N)Br
Chemical Name
Formula C10H9BrN2S M. Wt 269.16
Purity 98% Storage Store at 4-8°C
Description NS19504 is a selective activator of large-conductance Ca2+-activated potassium channels (BKCa, KCa1.1) (EC50 = 11 μM). Activates BK channels in native smooth muscle cells from guinea pig bladder and reduces spontaneous phasic contractions in bladder strips ex vivo. Displays no effect on contractions induced by a high K+ concentration or at 65 other receptors tested, including L- and N- type Ca2+ channels, Nav, KATP and hERG channels.
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