VU0134992
| CAS No. | 755002-90-5 | Cat. No. | BCP33228 |
| Name | VU0134992 | ||
| Synonyms | VU 992; VU992; VU-0134992; VU 0134992; VU0134992; | ||
| Formula | C20H31BrN2O2 | M. Wt | 411.38 |
| Description | VU0134992 is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 µM. VU0134992 is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel | ||
Structure
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