VU0134992 New
Data Sheet
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| CAS No. | 755002-90-5 | Cat. No. | BCP33228 |
| Name | VU0134992 | ||
| Synonyms | VU 992; VU992; VU-0134992; VU 0134992; VU0134992; | ||
| SMILES | CC(C)C1=CC(=C(C=C1)OCC(=O)NC2CC(NC(C2)(C)C)(C)C)Br | ||
| Chemical Name | |||
| Formula | C20H31BrN2O2 | M. Wt | 411.38 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | VU0134992 is the first subtype-preferring, orally active and selective Kir4.1 potassium channel pore blocker, with an IC50 of 0.97 µM. VU0134992 is 9-fold selective for homomeric Kir4.1 over Kir4.1/5.1 concatemeric channels (IC50=9 µM) at -120 mV. | ||
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