RS-127445 hydrochloride
| CAS No. | 199864-86-3 | Cat. No. | BCP36106 |
| Name | RS-127445 hydrochloride | ||
| Synonyms | RS 127445 hydrochloride; RS127445 hydrochloride; | ||
| Formula | C17H17ClFN3 | M. Wt | 317.79 |
| Description | RS-127445 is a selective, high affinity, orally bioavailable serotonin 5-HT2B receptor antagonist (pKi = 9.5), which displays 1000-fold selectivity for 5-HT2B with good bioavailability. In isolated human cells, RS 127445 exbhites an IC50 greater than 10uM. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor | ||
Structure
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