UCB-9260
| CAS No. | 1515888-53-5 | Cat. No. | BCP40717 |
| Name | UCB-9260 | ||
| Synonyms | UCB 9260;UCB9260; | ||
| Formula | C26H25N5O | M. Wt | 423.52 |
| Description | UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation. | ||
| Pathways | Apoptosis Pathway NFκB | ||
| Targets | TNF Receptor NF κB | ||
Structure
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