UCB-9260 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1515888-53-5 | Cat. No. | BCP40717 |
| Name | UCB-9260 | ||
| Synonyms | UCB 9260;UCB9260; | ||
| SMILES | CC1=CC(=C(C=C1)C)CN2C3=C(C=CC(=C3)C4=CN(N=C4)C)N=C2C(C5=CC=NC=C5)O | ||
| Chemical Name | |||
| Formula | C26H25N5O | M. Wt | 423.52 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | UCB-9260 is an orally active inhibitor that inhibits TNF signalling by stabilising an asymmetric form of the trimer. UCB-9260 binds TNF with Kd of 13 nM. UCB-9260 also inhibits NF-κB with IC50 of 202 nM after TNF stimulation. | ||
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