IMP-1088
CAS No. | 2059148-82-0 | Cat. No. | BCP42030 |
Name | IMP-1088 | ||
Synonyms | IMP 1088; IMP1088; | ||
Formula | C25H29F2N5O | M. Wt | 453.53 |
Description | IMP-1088 is an inhibitor of N-myristoyltransferase 1 (NMT1) and NMT2 (IC50 = <1 nM for both human enzymes). It prevents rhinoviral replication without inducing cytotoxicity, and inhibits co-translational myristoylation of a specific virus-encoded protein (VP0) to block viral capsid assembly. | ||
Pathways | Cell Cycle/DNA Damage | ||
Targets | DNA/RNA Synthesis |
Structure
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