IMP-1088

  • Chemical Properties
CAS No. 2059148-82-0 Cat. No. BCP42030
Name IMP-1088
Synonyms IMP 1088; IMP1088;
Formula C25H29F2N5O M. Wt 453.53
  • Biological Activity
Description IMP-1088 is an inhibitor of N-myristoyltransferase 1 (NMT1) and NMT2 (IC50 = <1 nM for both human enzymes). It prevents rhinoviral replication without inducing cytotoxicity, and inhibits co-translational myristoylation of a specific virus-encoded protein (VP0) to block viral capsid assembly.
Pathways Cell Cycle/DNA Damage 
Targets DNA/RNA Synthesis 

Structure

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