SCR130
| CAS No. | 2377858-38-1 | Cat. No. | BCP42678 |
| Name | SCR130 | ||
| Synonyms | SCR-130;SCR 130; | ||
| Formula | C19H13Cl2N3O2S | M. Wt | 418.30 |
| Description | SCR130 is a SCR7-based DNA nonhomologous end-joining (NHEJ) inhibitor. SCR130 inhibits the end-joining of DNA in a Ligase IV-dependent manner. SCR130 is specific to Ligase IV, and shows minimal or no effect on Ligase III and Ligase I mediated joining. SCR130 induces cell apoptosis and has anticancer activity. | ||
| Pathways | Cell Cycle/DNA Damage | ||
| Targets | DNA/RNA Synthesis | ||
Structure
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