m-PEG4-bromide
| CAS No. | 110429-45-3 | Cat. No. | BCP42805 |
| Name | m-PEG4-bromide | ||
| Synonyms | 13-Bromo-2,5,8,11-tetraoxatridecane;Triethylene Glycol 2-Bromoethyl Methyl Ether; | ||
| Formula | C9H19BrO4 | M. Wt | 271.15 |
| Description | m-PEG4-Br is a cleavable ADC linker used in the synthesis of antibody-drug conjugate (ADC) for Trastuzumab. m-PEG4-Br is placed distally from the monomethyl auristatin E (MMAE) payload to yield an ADC with altered hydrophilicity, antigen binding, and in vitro potency. m-PEG4-Br also can be used as a PROTAC linker that can be used in the synthesis of PROTACs. | ||
| Pathways | Others Pathway | ||
| Targets | ADC Related PROTAC | ||
Structure
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