CRMP2-Ubc9-NaV1.7 inhibitor 194

  • Chemical Properties
CAS No. 2241651-99-8 Cat. No. BCP44631
Name CRMP2-Ubc9-NaV1.7 inhibitor 194
Synonyms HUN51998; HUN-51998; HUN 51998;
Formula C34H31F2N3O3 M. Wt 567.62
  • Biological Activity
Description CRMP2-Ubc9-NaV1.7 inhibitor 194 is a CRMP2-Ubc9-NaV1.7 inhibitor. CRMP2-Ubc9-NaV1.7 inhibitor 194 was first descripted in patent WO 2018144900, which functioned as a antagonist of small ubiquitin like modifier (SUMO) related modification (SUMOylation) of collapsin response mediator protein 2 (CRMP2)​ with potential application for the treatment of voltage gated sodium channel 1.7 (Nav1.7) related itch, anosmia, migraine event, and​/or pain (e.g., neuropathic pain).
Pathways Ion Channel/Membrane Transporter 
Targets Sodium Channel 

Structure

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