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CRMP2-Ubc9-NaV1.7 inhibitor 194 Chemical Structure

CRMP2-Ubc9-NaV1.7 inhibitor 194

Data Sheet For research use only. Not for human use.
Cat. No. :BCP44631CAS No. :2241651-99-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2241651-99-8 Cat. No. BCP44631
Name CRMP2-Ubc9-NaV1.7 inhibitor 194
Synonyms HUN51998; HUN-51998; HUN 51998;
SMILES O=C(N1CCC(C2=NC3=CC=CC=C3N2CC4=CC=CC(F)=C4)CC1)C5=CC=C(OCC6=CC=CC(F)=C6)C(OC)=C5
Chemical Name
Formula C34H31F2N3O3 M. Wt 567.62
Purity 98% Storage Store at 4-8°C
Description CRMP2-Ubc9-NaV1.7 inhibitor 194 is a CRMP2-Ubc9-NaV1.7 inhibitor. CRMP2-Ubc9-NaV1.7 inhibitor 194 was first descripted in patent WO 2018144900, which functioned as a antagonist of small ubiquitin like modifier (SUMO) related modification (SUMOylation) of collapsin response mediator protein 2 (CRMP2)​ with potential application for the treatment of voltage gated sodium channel 1.7 (Nav1.7) related itch, anosmia, migraine event, and​/or pain (e.g., neuropathic pain).
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