PF-4479745
| CAS No. | 1065110-43-1 | Cat. No. | BCP45867 |
| Name | PF-4479745 | ||
| Synonyms | PF-04479745; PF04479745; PF 04479745; PF-4479745; PF4479745; PF 4479745; | ||
| Formula | C17H22N4 | M. Wt | 282.38 |
| Description | PF-4479745 is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measurable functional agonism at the key selectivity targets 5-HT2A and 5-HT2B in relevant tissue-based assay systems. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor | ||
Structure
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