SU16F
| CAS No. | 251356-45-3 | Cat. No. | BCP46277 |
| Name | SU16F | ||
| Synonyms | SU 16F;SU-16F; | ||
| Formula | C24H22N2O3 | M. Wt | 386.44 |
| Description | SU16F is a potent and selective PDGFRβ inhibitor with IC50s of 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively. Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase | ||
| Targets | PDGFR | ||
Structure
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