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SU16F Chemical Structure

SU16F

Data Sheet For research use only. Not for human use.
Cat. No. :BCP46277CAS No. :251356-45-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 251356-45-3 Cat. No. BCP46277
Name SU16F
Synonyms SU 16F;SU-16F;
SMILES CC1=C(NC(=C1CCC(=O)O)C)C=C2C3=C(C=C(C=C3)C4=CC=CC=C4)NC2=O
Chemical Name
Formula C24H22N2O3 M. Wt 386.44
Purity 98% Storage Store at 4-8°C
Description SU16F is a potent and selective PDGFRβ inhibitor with IC50s of 10 nM, 140 nM, 2.29 μM for PDGFRβ, PDGFR1, PDGFR2, respectively. Neutralization of PDGFRβ receptor by SU16f blocks the promoting role of GC-MSCs (gastric cancer-derived mesenchymal stem cells) conditioned medium in gastric cancer cell proliferation and migration.
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