Lapatinib ditosylate
| CAS No. | 388082-77-7 | Cat. No. | BCP47521 |
| Name | Lapatinib ditosylate | ||
| Synonyms | GSK572016; GSK-572016; GSK 572016; GW2016; GW-2016; GW 2016; | ||
| Formula | C43H42ClFN4O10S3 | M. Wt | 925.46 |
| Description | Lapatinib Ditosylate is the ditosylate salt of lapatinib, a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib is a synthetic, orally-active quinazoline with potential antineoplastic activity. Lapatinib reversibly blocks phosphorylation of the epidermal growth factor receptor (EGFR), ErbB2, and the Erk-1 and-2 and AKT kinases; it also inhibits cyclin D protein levels in human tumor cell lines and xenografts. EGFR and ErbB2 have been implicated in the growth of various tumor types. Check for active clinical trials or closed clinical trials using this agent. | ||
| Related Products | 388082-78-8（Lapatinib Ditosylate） 231277-92-2（Lapatinib） | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
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