Icenticaftor
| CAS No. | 1334546-77-8 | Cat. No. | BCP21194 |
| Name | Icenticaftor | ||
| Synonyms | QBW251; QBW 251; QBW-251; | ||
| Formula | C12H13F6N3O3 | M. Wt | 361.24 |
| Description | Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC50s of 79 nM and 497 nM for F508del and G551D CFTR, respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | CFTR | ||
Structure
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