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Icenticaftor Chemical Structure

Icenticaftor

Data Sheet For research use only. Not for human use.
Cat. No. :BCP21194CAS No. :1334546-77-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1334546-77-8 Cat. No. BCP21194
Name Icenticaftor
Synonyms QBW251; QBW 251; QBW-251;
SMILES CC(CNC(=O)C1=C(C=C(C(=N1)OC)C(F)(F)F)N)(C(F)(F)F)O
Chemical Name
Formula C12H13F6N3O3 M. Wt 361.24
Purity 98% Storage Store at 4-8°C
Description Icenticaftor (QBW251) is an orally active CFTR channel potentiator, with EC50s of 79 nM and 497 nM for F508del and G551D CFTR, respectively. Icenticaftor can be used for chronic obstructive pulmonary disease (COPD) and cystic fibrosis research.
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