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Tezacaftor Chemical Structure

Tezacaftor

Data Sheet For research use only. Not for human use.
Cat. No. :BCP07173CAS No. :1152311-62-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1152311-62-0 Cat. No. BCP07173
Name Tezacaftor
Synonyms VX 661; VX661;VX-661;
SMILES O=C(C1(C2=CC=C(OC(F)(F)O3)C3=C2)CC1)NC4=CC5=C(N(C[C@@H](O)CO)C(C(C)(C)CO)=C5)C=C4F
Chemical Name
Formula C26H27F3N2O6 M. Wt 520.5
Purity 98% Storage Store at 4-8°C
Description VX-661 is CFTR modulator. VX-661 is potentially useful for treatment of cystic fibrosis disease. Cystic fibrosis (CF) is a genetic disease caused by defects in the CF transmembrane regulator (CFTR) gene, which encodes an epithelial chloride channel. The most common mutation, Δ508CFTR, produces a protein that is misfolded and does not reach the cell membrane. VX-661 can correct trafficking of Δ508CFTR and partially restore chloride channel activity.
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