Candesartan
| CAS No. | 139481-59-7 | Cat. No. | BCP01137 |
| Name | Candesartan | ||
| Synonyms | Atacand; | ||
| Formula | C24H20N6O3 | M. Wt | 440.45 |
| Description | Candesartan binds with high specificity to the angiotensin II AT1 receptors in CHO-AT1 cells with K?1 of 0.001 min?1. Candesartan does not affect cell viability or proliferation but increases the expression of VEGF and interleukin-8 in the cultured medium of KU-19-19 cells. Candesartan (0.1 nM) could reduce the maximal contractile response to angiostensin II by approximately 50%. | ||
| Pathways | Protease/Metabolic Enzyme Hormone Pathay GPCR/G Protein | ||
| Targets | Angiotensin Receptor RAAS/ACE | ||
Structure
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