Ertugliflozin

  • Chemical Properties
CAS No. 1210344-57-2 Cat. No. BCP02525
Name Ertugliflozin
Synonyms PF-04971729;PF04971729;PF 04971729; PF-4971729; PF 4971729; PF4971729; PF-04971729-00; PF 04971729-00; PF04971729-00;
Formula C22H25ClO7 M. Wt 436.88
  • Biological Activity
Description Ertugliflozin, also known as also known as PF-04971729, is an inhibitor of sodium-glucose cotransporter 2 (SGLT2; IC50 = 0.927 nM for the human enzyme). clinical study showed that Ertugliflozin (1-25 mg/day) improved glycaemic control, body weight and blood pressure in patients with T2DM suboptimally controlled on metformin, and was well tolerated.
Pathways Ion Channel/Membrane Transporter GPCR/G Protein 
Targets SGLT 

Structure

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