Epinastine hydrochloride

CAS No.	80012-44-8	Cat. No.	BCP09495
Name	Epinastine hydrochloride
Synonyms	Alesion; Elestat; Epinastine HCl; Epinastin HCl;
Formula	C16H16ClN3	M. Wt	285.77

Description	Epinastine Hydrochloride is an histamine H1 receptor antagonist without sedative activity. Epinastine hydrochloride blocks the histamine H1 receptor and inhibits the release of histamine from mast cells. This prevents the typical allergic symptoms that are caused by histamine activity on capillaries, skin, mucous membranes. Typical histamine activities include vasodilation, bronchoconstriction, increased vascular permeability, pain, itching, and spasmodic contractions of gastrointestinal smooth muscles. Epinastine also has affinity for the histamine H2, 5-HT2, and the alpha-1, alpha-2 adrenergic receptors.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	Histamine Receptor

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