Pterosin B
| CAS No. | 34175-96-7 | Cat. No. | BCP09994 |
| Name | Pterosin B | ||
| Synonyms | Multifidoside B;(2R)-Pterosin B; | ||
| Formula | C14H18O2 | M. Wt | 218.29 |
| Description | Pterosin B is a salt-inducible kinase 3 (Sik3) pathway inhibitor, it prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3. Pterosin B has multiple targets in gluconeogenic programs, including coenzyme Q in RORα-SRC2 signaling. Pterosin B shows cytotoxicity against HL 60 cells (human leukemia) with the IC(50) value of 8.7 microg/mL. | ||
| Pathways | PI3K/Akt/mTOR Epigenetics | ||
| Targets | AMPK | ||
Structure
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