740Y-P
| CAS No. | 1236188-16-1 | Cat. No. | BCP16353 |
| Name | 740Y-P | ||
| Synonyms | 740 Y-P;740YP;740 YP;740YPDGFR; PDGFR 740Y-P；H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Ser-Asp-Gly-Gly-Tyr(PO3H2)-Met-Asp-Met-Ser-OH；RQIKIWFQNRRMKWKKSDGGXMDMS; | ||
| Formula | C141H222N43O39PS3 | M. Wt | 3270.72 |
| Description | 740 Y-P is a cell-permeable phosphopeptide activator of PI3K. It binds to the p85 N- and C-terminal SH2 domains of PI3K but not to GST or the N-terminal domain of phospholipase C (PLC) in an affinity purification assay. And it displays mitogenic activity in C2 muscle cells and promotes survival of rat cerebellar granule neurons in vitro. | ||
| Pathways | PI3K/Akt/mTOR | ||
| Targets | PI3K | ||
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AIM2 inhibits the proliferation, invasion and migration, and promotes the apoptosis of osteosarcoma cells by inactivating the PI3K/AKT/mTOR signaling pathway
Publications Citing of Biochempartner's 740Y-P(CAS:1236188-16-1) |
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Piceatannol Suppresses the Proliferation and Induced Apoptosis of Osteosarcoma Cells Through PI3K/AKT/mTOR Pathway
Publications Citing of Biochempartner's 740Y-P(CAS:1236188-16-1) |
Structure
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