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740Y-P Chemical Structure

740Y-P

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP16353CAS No. ：1236188-16-1Purity：98%
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  • Publications Citing of Biochempartner's 740Y-P
Mol Med Rep. 2022 Feb; 25(2): 53. Cancer Manag Res. 2020; 12: 2631–2640.
  • Chemical Properties&Biological Activity
CAS No. 1236188-16-1 Cat. No. BCP16353
Name 740Y-P
Synonyms 740 Y-P;740YP;740 YP;740YPDGFR; PDGFR 740Y-P；H-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-Ser-Asp-Gly-Gly-Tyr(PO3H2)-Met-Asp-Met-Ser-OH；RQIKIWFQNRRMKWKKSDGGXMDMS;
SMILES O=C(N[C@](C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CCCCN)C(N[C@](C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(NCC(NCC
Chemical Name
Formula C141H222N43O39PS3 M. Wt 3270.72
Purity 98% Storage Store at 4-8°C
Description 740 Y-P is a cell-permeable phosphopeptide activator of PI3K. It binds to the p85 N- and C-terminal SH2 domains of PI3K but not to GST or the N-terminal domain of phospholipase C (PLC) in an affinity purification assay. And it displays mitogenic activity in C2 muscle cells and promotes survival of rat cerebellar granule neurons in vitro.
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