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Umbralisib sulfate Chemical Structure

Umbralisib sulfate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24681CAS No. :1532533-75-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1532533-75-7 Cat. No. BCP24681
Name Umbralisib sulfate
Synonyms TGR-1202 sulfate; RP-5264 sulfate;
SMILES CC(C)OC1=C(C=C(C=C1)C2=NN(C3=NC=NC(=C23)N)C(C)C4=C(C(=O)C5=C(O4)C=CC(=C5)F)C6=CC(=CC=C6)F)F.OS(=O)(=O)O
Chemical Name
Formula C31H26F3N5O7S M. Wt 669.63
Purity 98% Storage Store at 4-8°C
Description Umbralisib sulfate is an orally active, potent and selective dual PI3Kδ and casein kinase-1-ε (CK1ε) inhibitor, with EC50 of 22.2 nM and 6.0 μM, respectively. Umbralisib sulfate exhibits unique immunomodulatory effects on chronic lymphocytic leukemia (CLL) T cells. Umbralisib sulfate can be used for haematological malignancies reseach.
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