DCPIB
| CAS No. | 82749-70-0 | Cat. No. | BCP30868 |
| Name | DCPIB | ||
| Synonyms | Dcpib;4-(2-butyl-6,7-dichlor-2-cyclopentyl-indan-1-on-5-yl) oxybutyric acid; | ||
| Formula | C22H28Cl2O4 | M. Wt | 427.36 |
| Description | DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC), voltage-dependently activates potassium channels TREK1 and TRAAK, inhibits TRESK, TASK1 and TASK3 (IC50s, 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM in CPAE cells. | ||
| Pathways | Ion Channel/Membrane Transporter | ||
| Targets | Potassium Channel Chloride Channel | ||
Structure
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