Fasudil hydrochloride hydrate

  • Chemical Properties
CAS No. 186694-02-0 Cat. No. BCP30939
Name Fasudil hydrochloride hydrate
Synonyms Fasudil hydrochloride hemihydrate;Fasudil HCl semihydrate;HA-1077; HA1077; HA 1077;
Formula C28H38Cl2N6O5S2 M. Wt 673.67
  • Biological Activity
Description Fasudil is a potent and selective Rho-kinase (ROCK) inhibitor and vasodilator. ROCK is an enzyme that participates in vasoconstriction and vascular remodeling. Fasudil is used for the treatment of cerebral vasospasm and has the potential to treat pulmonary hypertension as well as certain memory loss.
Pathways Cell Cycle/DNA Damage TGF beta/Smad  Wnt/Stem Cell 
Targets ROCK 

Structure

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