Theliatinib
| CAS No. | 1353644-70-8 | Cat. No. | BCP31409 |
| Name | Theliatinib | ||
| Synonyms | HMPL-309; HMPL 309; HMPL309;xiliertinibum; xiliertinib; | ||
| Formula | C25H26N6O2 | M. Wt | 442.51 |
| Description | Theliatinib is a novel small molecule, epidermal growth factor receptor tyrosine kinase inhibitor with potential antineoplastic and anti-angiogenesis activities. In vitro studies suggest that Theliatinib is a potent EGFR kinase inhibitor with good kinase selectivity and in vivo data demonstrated broad spectrum anti-tumor activity via oral dosing in multiple xerographs such as A-431, Bcap-37 and Fadu. | ||
| Pathways | Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway | ||
| Targets | EGFR | ||
Structure
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