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CAS No. | 1353644-70-8 | Cat. No. | BCP31409 |
Name | Theliatinib | ||
Synonyms | HMPL-309; HMPL 309; HMPL309;xiliertinibum; xiliertinib; | ||
SMILES | CN1CCC2C1CN(C2)C(=O)NC3=C(C=C4C(=C3)C(=NC=N4)NC5=CC=CC(=C5)C#C)OC | ||
Chemical Name | |||
Formula | C25H26N6O2 | M. Wt | 442.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Theliatinib is a novel small molecule, epidermal growth factor receptor tyrosine kinase inhibitor with potential antineoplastic and anti-angiogenesis activities. In vitro studies suggest that Theliatinib is a potent EGFR kinase inhibitor with good kinase selectivity and in vivo data demonstrated broad spectrum anti-tumor activity via oral dosing in multiple xerographs such as A-431, Bcap-37 and Fadu. |
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