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Theliatinib Chemical Structure

Theliatinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP31409CAS No. :1353644-70-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1353644-70-8 Cat. No. BCP31409
Name Theliatinib
Synonyms HMPL-309; HMPL 309; HMPL309;xiliertinibum; xiliertinib;
SMILES CN1CCC2C1CN(C2)C(=O)NC3=C(C=C4C(=C3)C(=NC=N4)NC5=CC=CC(=C5)C#C)OC
Chemical Name
Formula C25H26N6O2 M. Wt 442.51
Purity 98% Storage Store at 4-8°C
Description Theliatinib is a novel small molecule, epidermal growth factor receptor tyrosine kinase inhibitor with potential antineoplastic and anti-angiogenesis activities. In vitro studies suggest that Theliatinib is a potent EGFR kinase inhibitor with good kinase selectivity and in vivo data demonstrated broad spectrum anti-tumor activity via oral dosing in multiple xerographs such as A-431, Bcap-37 and Fadu.
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