MRTX849 acid

  • Chemical Properties
CAS No. 2561529-96-0 Cat. No. BCP44575
Name MRTX849 acid
Synonyms
Formula C34H37ClFN7O4 M. Wt 662.15
  • Biological Activity
Description MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2. LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50s between 0.25 and 0.76 μM).
Related Products 2490716-96-4(MRTX849 analog 24) 2326521-71-3(MRTX849 )
Pathways GPCR/G Protein 
Targets Ras/Rho 

Structure

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