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MRTX849 acid Chemical Structure

MRTX849 acid

Data Sheet For research use only. Not for human use.
Cat. No. :BCP44575CAS No. :2561529-96-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2561529-96-0 Cat. No. BCP44575
Related Products 2490716-96-4(MRTX849 analog 24) 2326521-71-3(MRTX849 )
Name MRTX849 acid
Synonyms
SMILES C=C(C(=O)N1CCN(CC1CC#N)C2=NC(=NC3=C2CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)OCC6CCCN6CCC(=O)O)F
Chemical Name
Formula C34H37ClFN7O4 M. Wt 662.15
Purity 98% Storage Store at 4-8°C
Description MRTX849 acid, a derivative of MRTX849, can be used in the synthesis of PROTAC LC-2. LC-2 is a potent and first-in-class PROTAC capable of degrading endogenous KRAS G12C (DC50s between 0.25 and 0.76 μM).
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