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ASP2453 Chemical Structure

ASP2453

Data Sheet For research use only. Not for human use.
Cat. No. :BCP48490CAS No. :2241719-73-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2241719-73-1 Cat. No. BCP48490
Name ASP2453
Synonyms ASP 2453; ASP-2453;
SMILES CC1=C(C2=C(C=C1)NN=C2)C3=C(C=C4C(=C3OCC(F)(F)F)N=C(N=C4N5CCC6(CC5)CN(C6)C(=O)C=C)OC7CCN(CC7)CCCOC)C8CC8
Chemical Name
Formula C40H48F3N7O4 M. Wt 747.85
Purity 98% Storage Store at 4-8°C
Description ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
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