WYE-687

  • Chemical Properties
CAS No. 1062161-90-3 Cat. No. BCP23427
Name WYE-687
Synonyms WYE 687;WYE687;
Formula C28H32N8O3 M. Wt 528.61
  • Biological Activity
Description WYE-687 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.
Pathways PI3K/Akt/mTOR 
Targets PI3K mTOR 

Structure

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