WYE-687
CAS No. | 1062161-90-3 | Cat. No. | BCP23427 |
Name | WYE-687 | ||
Synonyms | WYE 687;WYE687; | ||
Formula | C28H32N8O3 | M. Wt | 528.61 |
Description | WYE-687 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively. | ||
Pathways | PI3K/Akt/mTOR | ||
Targets | PI3K mTOR |
Structure
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