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WYE-687 Chemical Structure

WYE-687

Data Sheet For research use only. Not for human use.
Cat. No. :BCP23427CAS No. :1062161-90-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1062161-90-3 Cat. No. BCP23427
Name WYE-687
Synonyms WYE 687;WYE687;
SMILES COC(=O)NC1=CC=C(C=C1)C2=NC3=C(C=NN3C4CCN(CC4)CC5=CN=CC=C5)C(=N2)N6CCOCC6
Chemical Name
Formula C28H32N8O3 M. Wt 528.61
Purity 98% Storage Store at 4-8°C
Description WYE-687 is an ATP-competitive mTOR inhibitor with an IC50 of 7 nM. WYE-687 concurrently inhibits activation of mTORC1 and mTORC2. WYE-687 also inhibits PI3Kα and PI3Kγ with IC50s of 81 nM and 3.11 μM, respectively.
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