Erismodegib
| CAS No. | 956697-53-3 | Cat. No. | BCP02275 |
| Name | Erismodegib | ||
| Synonyms | LDE225;LDE-225;NVP-LDE225;Sonidegib; NVP-LDE-225; NVP LDE225; | ||
| Formula | C26H26F3N3O3 | M. Wt | 485.5 |
| Description | Sonidegib, also known as, erismodegib, LDE225, NVP-LDE225, is an orally bioavailable small-molecule Smoothened (Smo) antagonist with potential antineoplastic activity. Erismodegib selectively binds to the Hedgehog (Hh)-ligand cell surface receptor Smo, which may result in the suppression of the Hh signaling pathway and, so, the inhibition of tumor cells in which this pathway is abnormally activated. | ||
| Pathways | GPCR/G Protein Wnt/Stem Cell | ||
| Targets | Smoothened/Smo Hedgehog | ||
Structure
Part data of this page collected from the open network resources, so Biochempartner can not guarantee its accuracy.
For product details of different batches, please contact our Customer
- Service & Tech Support:orders@biochempartner.com
- Website:www.biochempartner.com
Products are for research use only and not for human use. We do not sell to patients.