AZD-8931 Difumaric acid

  • Chemical Properties
CAS No. 1196531-39-1 Cat. No. BCP24789
Name AZD-8931 Difumaric acid
Synonyms AZD 8931 Difumaric acid;AZD8931 Difumaric acid;Sapitinib Difumaric acid;
Formula C31H33ClFN5O11 M. Wt 706.07
  • Biological Activity
Description AZD-8931 is an erbB receptor tyrosine kinase inhibitor with potential antineoplastic activity. erbB kinase inhibitor AZD8931 binds to and inhibits erbB tyrosine receptor kinases, which may result in the inhibition of cellular proliferation and angiogenesis in tumors expressing erbB. The erbB protein family, also called the epidermal growth factor receptor (EGFR) family, plays major roles in tumor cell proliferation and tumor vascularization.
Pathways Angiogenesis/Protein Tyrosine Kinase Jak/Stat Pathway 
Targets EGFR HER2 

Structure

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