(−)-Nutlin-3
| CAS No. | 548472-68-0 | Cat. No. | BCP29278 |
| Name | (−)-Nutlin-3 | ||
| Synonyms | (±)-Nutlin-3, Nutlin-3, Nutlin 3; | ||
| Formula | C30H30Cl2N4O4 | M. Wt | 581.49 |
| Description | Nutlin 3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells. | ||
| Pathways | Apoptosis Pathway | ||
| Targets | Mdm2 p53 | ||
Structure
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