(−)-Nutlin-3 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 548472-68-0 | Cat. No. | BCP29278 |
| Name | (−)-Nutlin-3 | ||
| Synonyms | (±)-Nutlin-3, Nutlin-3, Nutlin 3; | ||
| SMILES | CC(C)OC1=C(C=CC(=C1)OC)C2=NC(C(N2C(=O)N3CCNC(=O)C3)C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl | ||
| Chemical Name | |||
| Formula | C30H30Cl2N4O4 | M. Wt | 581.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Nutlin 3 is a potent and selective Mdm2 (RING finger-dependent ubiquitin protein ligase for itself and p53) antagonist with IC50 of 90 nM in a cell-free assay; stabilizes p73 in p53-deficient cells. | ||
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