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MX69 Chemical Structure

MX69

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP19296CAS No. ：1005264-47-0Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1005264-47-0 Cat. No. BCP19296
Name MX69
Synonyms MX-69;MX 69;
SMILES
Chemical Name
Formula C27H26N2O4S M. Wt 474.57
Purity 98% Storage Store at 4-8°C
Description MX69 blocks the MDM2 protein-XIAP RNA interaction, leading to MDM2 degradation. MX69 shows minimal inhibitory effect on normal human hematopoiesis in vitro and is very well tolerated in animal models. MX69-induced MDM2 downregulation results not only in inhibition of XIAP expression, but also in activation of p53, which contributes to cancer cell apoptosis in vitro and inhibition of cancer cell proliferation in vivo.
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