Pimethixene

CAS No.	314-03-4	Cat. No.	BCP43719
Name	Pimethixene
Synonyms	Pimetixene; BP 400; BP-400; BP400; Calmixene;
Formula	C19H19NS	M. Wt	293.43

Description	Pimethixene is antihistamine and antiserotonergic compound, acts as an antimigraine agent. Pimethixene is a highly potent antagonist of 5-HT1A, 5-HT2A, 5-HT2B, 5-HT2C, histamine H1, dopamine D2 and D4.4 as well as muscarinic M1 and M2 receptors, with pKis of 7.63, 10.22, 10.44, 8.42, 10.14, 8.19, 7.54, 8.61 and 9.38, respectively.
Pathways	Neuro Signaling Pathway GPCR/G Protein
Targets	5 HT Receptor/Serotonin Receptor Histamine Receptor

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