ML 145
| CAS No. | 1164500-72-4 | Cat. No. | BCP45167 |
| Name | ML 145 | ||
| Synonyms | ML-145; ML145; | ||
| Formula | C24H22N2O5S2 | M. Wt | 482.57 |
| Description | ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM. ML 145 has over 1000-fold more selective for GPR35 compared to GPR55 (IC50/EC50=21.7 μM). ML 145 has no significant activity for GPR35 at either rodent ortholog. | ||
| Pathways | Hormone Pathay GPCR/G Protein | ||
| Targets | CXCR GPR | ||
Structure
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