ML 145 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1164500-72-4 | Cat. No. | BCP45167 |
| Name | ML 145 | ||
| Synonyms | ML-145; ML145; | ||
| SMILES | CC(=CC1=CC=CC=C1)C=C2C(=O)N(C(=S)S2)CCCC(=O)NC3=CC(=C(C=C3)C(=O)O)O | ||
| Chemical Name | |||
| Formula | C24H22N2O5S2 | M. Wt | 482.57 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ML 145 is a selective and competitive human GPR35/CXCR8 antagonist with an IC50/EC50 of 20.1 nM. ML 145 has over 1000-fold more selective for GPR35 compared to GPR55 (IC50/EC50=21.7 μM). ML 145 has no significant activity for GPR35 at either rodent ortholog. | ||
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