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ALX 40-4C Chemical Structure

ALX 40-4C

Data Sheet For research use only. Not for human use.
Cat. No. :BCP34188CAS No. :143413-49-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 143413-49-4 Cat. No. BCP34188
Name ALX 40-4C
Synonyms ALX-40-4C;ALX40-4C;Ac-(D-Arg)9-NH2;N-alpha-Acetyl-nona-D-arginine amide acetate;
SMILES
Chemical Name
Formula C56H113N37O10 M. Wt 1464.74
Purity 98% Storage Store at 4-8°C
Description ALX 40-4C is a small peptide inhibitor of the chemokine receptor CXCR4, interacts with the second extracellular loop of CXCR4 and inhibits infection exclusively by blocking direct virus-CXCR4 interactions. ALX 40-4C shows potent anti HIV-1 effect, with EC50s of 0.34 ± 0.04 μg/mL, 0.37 ± 0.01 μg/mL for HIV-1 NL4-3, NC10, and 0.18 ± 0.11 μg/mL, 0.06 ± 0.02 μg/mL for HIV-1 HXB2, HC43, respectively, and with a CC50 (50% cytotoxic concentration) of 21 μg/mL.
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