WAY-181187 hydrochloride
| CAS No. | 554403-08-6 | Cat. No. | BCP45356 |
| Name | WAY-181187 hydrochloride | ||
| Synonyms | WAY-181187 HCl;WAY181187 HCl;WAY 181187 HCl; | ||
| Formula | C15H14Cl2N4O2S2 | M. Wt | 417.32 |
| Description | WAY-181187 is a potent and selective 5-HT6 receptor agonist. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%). In the rat frontal cortex, acute administration of WAY-181187 (3-30 mg/kg, subcutaneous (s.c.)) significantly increased extracellular GABA concentrations without altering the levels of glutamate or norepinephrine. | ||
| Pathways | Neuro Signaling Pathway GPCR/G Protein | ||
| Targets | 5 HT Receptor/Serotonin Receptor | ||
Structure
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