WAY-181187 hydrochloride New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 554403-08-6 | Cat. No. | BCP45356 |
| Name | WAY-181187 hydrochloride | ||
| Synonyms | WAY-181187 HCl;WAY181187 HCl;WAY 181187 HCl; | ||
| SMILES | C1=CC=C2C(=C1)C(=CN2S(=O)(=O)C3=C(N=C4N3C=CS4)Cl)CCN.Cl | ||
| Chemical Name | |||
| Formula | C15H14Cl2N4O2S2 | M. Wt | 417.32 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | WAY-181187 is a potent and selective 5-HT6 receptor agonist. WAY-181187 possesses high affinity binding (2.2 and 4.8 nM, respectively) at the human 5-HT6 receptor and profile as full receptor agonists (WAY-181187: EC50=6.6 nM, Emax=93%). In the rat frontal cortex, acute administration of WAY-181187 (3-30 mg/kg, subcutaneous (s.c.)) significantly increased extracellular GABA concentrations without altering the levels of glutamate or norepinephrine. | ||
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